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Phospho-ATR (Thr1989) Monoclonal Antibody (GT222), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA527731
This item is not returnable.
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Description
Positive Control: HCT116, HCT116(100 J/m2 UVC and recover for 6hr) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Specifications
| Phospho-ATR (Thr1989) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 20% glycerol and no preservative; pH 7 | |
| Q13535 | |
| ATR | |
| Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATR (phospho Thr1989). The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Immunocytochemistry, Immunoprecipitation, Western Blot | |
| GT222 | |
| Unconjugated | |
| ATR | |
| 2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8 | |
| Mouse | |
| Protein A | |
| RUO | |
| 545 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |