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Thermo Scientific™ MT(PEG)4 Methyl-PEG-Thiol Compound
MT(PEG)n: methyl and sulfhydryl compound with a 4-unit polyethylene glycol (PEG) spacer; methylate and pegylate quantum dots, gold surfaces, silver.
Brand: Thermo Scientific™ 26132
Description
Thermo Scientific™ Pierce MT(PEG)4, or methyl-PEG4-thiol, is a methyl- and sulfhydryl-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic particles.
MT(PEG)4 is monodentate thiol-terminated and methyl pegylation reagent. The PEG compound has a defined molecular weight and spacer length and is useful for modifying surfaces such quantum dots, self-assembled monolayers and magnetic particles. Functionalization of solid surfaces with polyethylene glycol spacers such as this one significantly reduces nonspecific protein binding.Highlights:
Metal-binding – terminal monodentate thiol reacts spontaneously with gold surfaces through dative binding
Methyl – terminal methyl group is unreactive, the primary function of this compound being to coat quantum dot and other surfaces to reduce nonspecific binding in assays
Polyethylene glycol – PEG groups are flexible, non-immunogenic, hydrophilic, and significantly reduce nonspecific binding of surfaces for protein methods
Spacer arm – four-unit PEG spacer makes compound nearly 16 angstroms long
Specifications:
- Alternative name: Methyl-PEG4-Thiol
- Chemical name: 2,5,8,11-tetraoxatridecane-13-thiol
- Chemical formula: C9H20O4S
- Molecular weight: 224.32
- Spacer arm: 15.8 angstroms
- Form: clear colorless to light yellow liquid
- Solubility: dissolve in DMSO or DMF for use
Specifications
Metal Surface | |
Polyethylene Glycol (PEG), Blocking Groups | |
4 ethylene glycol units | |
100 mg | |
Thiol Compound |
Upon receipt store at -20°C protected from moisture. Products shipped at ambient temperature. | |
Carboxylic Acid, Thiol | |
Liquid | |
DMF or DMSO |
For Research Use Only. Not for use in diagnostic procedures.