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Thermo Scientific™ SIA (succinimidyl iodoacetate)
Crosslink amines to sulfhydryls with this very short crosslinker composed of NHS-ester and iodoacetyl (haloacetyl) groups at ends of a 3-atom (1.5A) spacer arm.
Brand: Thermo Scientific™ 22349
86.45 EUR valid until 2025-05-31
Use promo code "25977" to get your promotional price.
Description
Thermo Scientific™ Pierce SIA is a very short (1.5 Å) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.
Suited to capturing amine and sulfhydryl groups in very close proximityHighlights:
- Reactive groups: NHS ester and iodoacetyl
- Reactive toward: amino and sulfhydryl groups

Specifications
Amine-Sulfhydryl | |
SIA | |
No | |
Upon receipt store at 4°C protected from moisture. | |
Ambient | |
Chemical Labeling | |
Haloacetyl, NHS Ester | |
Solid | |
DMF, DMSO | |
No |
No | |
283.02 | |
1.5 Å | |
Yes | |
Pierce™ | |
Heterobifunctional | |
Short (<10 Å) | |
50 mg | |
Standard | |
Crosslinker |
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Safety and Handling
- SIA (succinimidyl iodoacetate)
Signal Word
- Warning
Hazard Category
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
Precautionary Statement
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
Supplemental information
- MIXTURE LIST-Contains : N-Hydroxysuccinimidyl iodoacetate
Certificates
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For Research Use Only. Not for use in diagnostic procedures.