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Specifications
| Chemical Reactivity | Amine-Sulfhydryl |
|---|---|
| Cleavable | By Thiols |
| Molecular Weight (g/mol) | 334.32 |
| PEGylated | No |
| Spacer Arm Length | 8.3 Å |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
10066813
|
Thermo Scientific™
22360 |
50 mg |
157.00€
50mg |
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|
15890853
|
Thermo Scientific™
A35394 |
10 x 1 mg |
165.00€
Pack of 10 |
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Description
Thermo Scientific™ Pierce SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 Ås).
Highlights:
- Cyclohexane bridge adds stability to the maleimide-reactive group; N-(4-carboxycyclohexylmethyl) maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7.0 at 4°C
- Ideal for coupling enzymes to antibodies
- Reactive groups: NHS-ester and maleimide
- Reactive toward: amino and sulfhydryl groups
Specifications
| Amine-Sulfhydryl | |
| 334.32 | |
| 8.3 Å | |
| Yes | |
| Chemical Labeling | |
| Maleimide, NHS Ester | |
| Powder | |
| Standard, Single-use | |
| Crosslinker |
| By Thiols | |
| No | |
| Upon receipt store desiccated at 4°C. | |
| Ambient | |
| Heterobifunctional | |
| Short (<10 Å) | |
| DMF, DMSO | |
| No |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- SMCC
Signal Word
- Warning
Hazard Category
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
Precautionary Statement
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P264-Wash hands thoroughly after handling.
- P271-Use only outdoors or in a well-ventilated area.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
- P362+P364-Take off contaminated clothing and wash it before reuse.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : Succinimidyl-trans-4-(N-maleimidylmethyl)cyclohexane-1-carboxylate
For Research Use Only. Not for use in diagnostic procedures.
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Product Title
Thermo Scientific™ Pierce™ SMCC