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Tocris Bioscience™ Pyridostatin pentahydrochloride

Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest

308.00€

Specifications

CAS 1781882-65-2
Product Type Pyridostatin pentahydrochloride
Inhibitors Pyridostatin pentahydrochloride
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Product Code Brand Quantity Price Quantity & Availability  
18744719
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Tocris Bioscience™
4763/10 		10 mg
308.00€
10mg
Estimated Shipment: 29-01-2025
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Description

Description

Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells. Also targets telomeric G-quadruplexes, inducing telomerase dysfunction. Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).
Specifications

Specifications

1781882-65-2
Pyridostatin pentahydrochloride
Pyridostatin pentahydrochloride
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