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  7. (R)-(-)-α-Methylhistamine dihydrobromide, Tocris Bioscience™

(R)-(-)-α-Methylhistamine dihydrobromide, Tocris Bioscience™

Product Code. 30001101
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Quantity:
10 mg
50 mg
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Description

Potent, standard H3 agonist

Very potent, high affinity H3 agonist (KD = 50.3 nM) that displays > 200-fold selectivity over H4 receptors. Inhibits H3-mediated histamine synthesis and release in the CNS and stimulates H4-mediated eosinophil shape change (EC50 = 66 nM).

S-enantiomer also available.

Chemical Identifiers

CAS 868698-49-1
Molecular Formula C6H13Br2N3
Molecular Weight (g/mol) 286.999
InChI Key RWHNAAABSGVRDT-ZJIMSODOSA-N
Synonym r---alpha-methylhistamine dihydrobromide, r---?-methylhistamine dihydrobromide, r---, a-methylhistamine dihydrobromide, r---alpha-methylhisamine dihydrochloride, r-1-1h-imidazol-4-yl propan-2-amine dihydrobromide, r---?-methyl-1h-imidazole-4-ethanamine dihydrobromide, 2r-1-1h-imidazol-4-yl propan-2-amine dihydrobromide
PubChem CID 45037031
IUPAC Name (2R)-1-(1H-imidazol-5-yl)propan-2-amine;dihydrobromide
SMILES CC(CC1=CN=CN1)N.Br.Br

Specifications

Quantity 10 mg
Formula Weight 287
Percent Purity >99%
Chemical Name or Material (R)-(-)-α-Methylhistamine dihydrobromide
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