missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Lipids and Lipid Derivatives
  5. Fatty acid conjugates
  6. (S)-(+)-Dimethindene maleate, Tocris Bioscience™

(S)-(+)-Dimethindene maleate, Tocris Bioscience™

Product Code. 18782604
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

M2-selective antagonist

(S)-(+)-Dimethindene maleate is an enantiomer that is a subtype-selective M2 muscarinic receptor antagonist (pKi values are 7.08, 7.78, 6.70 and 7.00 for M1, M2, M3 and M4 receptors respectively). Also H1 histamine receptor antagonist (pKi = 7.48). Allows formation of extended pluripotent stem (EPS) cells in combination with CHIR 99021 (Cat.No. 4423), minocycline hydrochloride (Cat.No. 3268) and human leukemia inhibitory factor.

For more information about how Dimethindene maleate may be used, see our protocol: Generation and Propagation of EPS cells (LCDM Cocktail) .

Chemical Identifiers

CAS 136152-65-3
Molecular Formula C24H28N2O4
Molecular Weight (g/mol) 408.498
InChI Key SWECWXGUJQLXJF-HFNHQGOYSA-N
Synonym s-+-dimethindene maleate, unii-j43zl3wtln, dimethindene maleate, +, j43zl3wtln, dsstox_cid_28966, dsstox_rid_83231, dsstox_gsid_49040, dimethindene maleate, s-+, d0zj1c, 1h-indene-2-ethanamine, n,n-dimethyl-3-1s-1-2-pyridinyl ethyl-, 2z-2-butenedioate 1:1
PubChem CID 56972160
IUPAC Name (Z)-but-2-enedioic acid;N,N-dimethyl-2-[3-[(1S)-1-pyridin-2-ylethyl]-1H-inden-2-yl]ethanamine
SMILES CC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C.C(=CC(=O)O)C(=O)O

Specifications

Quantity 10 mg
Formula Weight 408.5
Percent Purity >99%
Chemical Name or Material (S)-(+)-Dimethindene maleate
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.