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SDZ NKT 343

Highly selective, human NK1 antagonist

Brand:  Tocris Bioscience 2394/10

Product Code. 18015042

  • 272.00€ / 10mg

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Description

Description

Highly selective human tachykinin NK1 receptor antagonist (IC50 values are 0.62 and 451 nM for human and rat receptors respectively) that displays > 130-fold selectivity over human NK2 and NK3 receptors. Potently antagonizes SP-induced Ca2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

>98%
Store at +4°C
SDZ NKT 343
180046-99-5
579.657
10 mg
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