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SR 8278, Tocris Bioscience™

Product Code. 30001608
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Rev-Erbα antagonist

Rev-Erbα antagonist; inhibits Rev-Erbα transcriptional repression (EC50 = 0.47 μM). Blocks activity of Rev-Erbα agonist GSK 4112 (Cat. No. 3663) in HEK293 cells. Increases expression of glucose-regulating genes, G6Pase and PEPCK in HepG2 cells.

Chemical Identifiers

CAS 1254944-66-5
Molecular Formula C18H19NO3S2
Molecular Weight (g/mol) 361.474
InChI Key UIEBLUZPSFAFOC-UHFFFAOYSA-N
Synonym 1,2,3,4-tetrahydro-2-5-methylthio-2-thienyl carbonyl-3-isoquinolinecarboxylic acid ethyl ester, ethyl 2-5-methylsulfanyl thiophene-2-carbonyl-3,4-dihydro-1h-isoquinoline-3-carboxylate, d0k1vv, sr, semisolid, ethyl 2-5-methylsulfanyl thiophene-2-carbonyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate, ethyl 2-5-methylsulfanyl thiophen-2-yl carbonyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
PubChem CID 53393127
IUPAC Name ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate
SMILES CCOC(=O)C1CC2=CC=CC=C2CN1C(=O)C3=CC=C(S3)SC

Specifications

Quantity 50 mg
Formula Weight 361.48
Percent Purity >99%
Chemical Name or Material SR 8278
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