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STEMCELL Technologies Tamoxifen
Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor

394.20€ - 2382.75€
Specifications
CAS | 10540-29-1 |
---|---|
Synonym | trans-Tamoxifen |
Molecular Formula | C26H29NO |
Purity | ≥95% |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17140102
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STEMCELL Technologies
72662 |
500 mg |
394.20€
500mg |
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17150102
![]() |
STEMCELL Technologies
72664 |
5 g |
1317.60€
5g |
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17160102
![]() |
STEMCELL Technologies
72666 |
10 g |
2382.75€
10g |
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Description
- Tamoxifen is a selective estrogen receptor modulator (SERM), with tissue-specific antagonistic or agonistic effects
- Receptor activation leads to the formation of homo- and hetero-dimers, which in turn interact with accessory proteins to regulate gene transcription
- Tamoxifen is commonly used to activate Cre-ER in transgenic conditional models
- Used in transgenic models to induce Cre-mediated recombination in conjunction with Cre-ER, a fusion protein consisting of Cre recombinase and a mutant form of the estrogen receptor hormone-binding domain that specifically binds tamoxifen but not estrogen (Feil et al.; Zhang et al.)
- Inhibits growth in the human breast cancer cell line, MCF-7 (Katzenellenbogen et al.)
- Antagonist of estrogen receptor action in breast tissue and breast cancer cells (Abe et al.; Horwitz et al.)
Specifications
10540-29-1 | |
trans-Tamoxifen | |
C26H29NO | |
≥95% |
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Product Title
STEMCELL Technologies Tamoxifen