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TC-MCH 7c, Tocris Bioscience™

Product Code. 30001499
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Quantity:
10 mg
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This item is not returnable. View return policy

Description

Selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist

Potent, selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist (IC50= 5.6 nM in hMCH1R-expressing CHO cells). Displays selectivity for MCH1R over MCH2R (IC50 = > 10 μM). Decreases body weight in a mouse model of diet-induced obesity. Brain penetrant; orally active.

Specifications

CAS 864756-35-4
Molecular Formula C24H25FN2O3
Quantity 10 mg
Synonym tc-mch 7c, 4-4-fluorobenzyloxy-1-4-2-pyrrolidin-1-yl ethoxy phenyl pyridin-2 1h-one, 4-4-fluorophenyl methoxy-1-4-2-1-pyrrolidinyl ethoxy phenyl-2 1h-pyridinone
InChI Key ANCFKYJMXNMYNZ-UHFFFAOYSA-N
SMILES C1CCN(C1)CCOC2=CC=C(C=C2)N3C=CC(=CC3=O)OCC4=CC=C(C=C4)F
IUPAC Name 4-[(4-fluorophenyl)methoxy]-1-[4-(2-pyrrolidin-1-ylethoxy)phenyl]pyridin-2-one
Molecular Weight (g/mol) 408.473
PubChem CID 11654412
Formula Weight 408.47
Percent Purity >97%
Chemical Name or Material TC-MCH 7c
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