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TPMPA, Tocris Bioscience™

Product Code. 30002159
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective GABAA-ρ antagonist

A selective, competitive GABAA-ρ antagonist with only minimal effects on GABAA and GABAB receptors (Kb values are 2.1 μM (antagonist), 320 μM (antagonist) and EC50 ∽ 500 μM (weak agonist) respectively). Displays 8-fold selectivity for human recombinant ρ1 receptors over ρ2 receptors.

Chemical Identifiers

CAS 182485-36-5
Molecular Formula C6H12NO2P
Molecular Weight (g/mol) 161.141
InChI Key MFUKVPOVVKKLRQ-UHFFFAOYSA-N
Synonym tpmpa, methyl 1,2,3,6-tetrahydropyridin-4-yl phosphinic acid, unii-tr7i0800l2, phosphinic acid, p-methyl-p-1,2,3,6-tetrahydro-4-pyridinyl, 1,2,5,6-tetrahydropyridin-4-yl methylphosphinic acid hydrate, tpmpa mi, methyl 1,2,3,6-tetrahydropyridinium-4-yl phosphinate, biomol-nt_000236, p-methyl-p-1,2,3,6-tetrahydro-4-pyridinyl phosphinic acid, 1,2,5,6-tetrahydropyridin-4-yl methylphosphinsaure
PubChem CID 5521
IUPAC Name methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
SMILES CP(=O)(C1=CCNCC1)O

Specifications

Quantity 50 mg
Formula Weight 161.14
Percent Purity >98%
Chemical Name or Material TPMPA
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