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Trifluoromethanesulfonic acid, 98+%, Thermo Scientific Chemicals
Description
Trifluoromethanesulfonic acid acts as a catalyst for esterification reactions and an acidic titrant in nonaqueous acid-base titration. It is useful in protonations due to the presence of conjugate base triflate is non nucleophilic. It serves as a deglycosylation agent for glycoproteins. In addition, it is a precursor and a catalyst in organic chemistry. It reacts with acyl halides to prepare mixed triflate anhydrides, which are strong acylating agents used in Friedel-Crafts reactions. It acts as a key starting material for the preparation of ethers and olefins by reacting with alcohols as well as to prepare trifluoromethanesulfonic anhydride by dehydration reaction.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Trifluoromethanesulfonic acid acts as a catalyst for esterification reactions and an acidic titrant in nonaqueous acid-base titration. It is useful in protonations due to the presence of conjugate base triflate is non nucleophilic. It serves as a deglycosylation agent for glycoproteins. In addition, it is a precursor and a catalyst in organic chemistry. It reacts with acyl halides to prepare mixed triflate anhydrides, which are strong acylating agents used in Friedel-Crafts reactions. It acts as a key starting material for the preparation of ethers and olefins by reacting with alcohols as well as to prepare trifluoromethanesulfonic anhydride by dehydration reaction.
Solubility
Miscible with water, dimethyl sulfoxide, dimethyl formamide and acetonitrile.
Notes
Hygroscopic. Incompatible with strong oxidizing agents, strong bases, water and metals.
Specifications
Specifications
| Melting Point | -40°C |
| Density | 1.708 |
| Boiling Point | 161°C to 162°C |
| Flash Point | None |
| Odor | Pungent |
| Linear Formula | CF3SO3H |
| Refractive Index | 1.327 |
| Quantity | 10 g |
| UN Number | UN3265 |
| Beilstein | 1812100 |
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Safety and Handling
- Trifluoromethanesulfonic acid
- Danger
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 1
- Substances and mixtures corrosive to metals Category 1
- Skin corrosion/irritation Category 1 B
- Specific target organ toxicity Category 3
- H290-May be corrosive to metals.
- H302-Harmful if swallowed.
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H335-May cause respiratory irritation.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : Trifluoromethanesulfonic acid
RUO – Research Use Only