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  7. Trovafloxacin mesylate, Tocris Bioscience™

Trovafloxacin mesylate, Tocris Bioscience™

Product Code. 18722694
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Quantity:
10 mg
50 mg
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Description

Antibiotic; inhibits bacterial DNA synthesis

Fluoroquinolone antibiotic. Inhibits bacterial DNA topoisomerase IV and DNA gyrase and forms a stable quinolone-DNA complex with these enzymes which reversibly inhibits DNA synthesis. Displays potent activity against gram-positive and gram-negative bacteria. Increases the production of mitochondrial NO in immortalized hepatocytes; also increases mitochondrial Ca2+. Inhibits Panx-1 (IC50 ∽ 4μM).

Chemical Identifiers

CAS 147059-75-4
Molecular Formula C21H19F3N4O6S
Molecular Weight (g/mol) 512.46
InChI Key DYNZICQDCVYXFW-GIPYJWDTSA-N
Synonym trovafloxacin mesylate, trovan, trovafloxacin monomethanesulfonate, trovafloxacin methanesulfonate, unii-0p1lko80wn, 0p1lko80wn, trovafloxacin mesylate usan, trovan tn, trovafloxacin mesilate, dsstox_cid_25701
PubChem CID 62960
IUPAC Name 7-[(1S,5R)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid
SMILES CS(=O)(=O)O.C1C2C(C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F

Specifications

Quantity 50 mg
Formula Weight 512.46
Percent Purity >99%
Chemical Name or Material Trovafloxacin mesylate
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