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VU 10010, Tocris Bioscience™

Product Code. 18025522
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Selective allosteric potentiator of M4 receptors

Selective allosteric potentiator of M4 acetylcholine receptors (EC50 values are 33 and 0.7 nM for ACh in the absence and presence of VU10010 respectively). Binds to an allosteric site on the receptor increasing affinity for ACh and coupling to G-proteins.

Chemical Identifiers

CAS 633283-39-3
Molecular Formula C17H16ClN3OS
Molecular Weight (g/mol) 345.845
InChI Key FPRULFHDSFKYBV-UHFFFAOYSA-N
Synonym 3-amino-n-4-chlorophenyl methyl-4,6-dimethylthieno 2,3-b pyridine-2-carboxamide, 3-amino-n-4-chlorobenzyl-4,6-dimethylthieno 2,3-b pyridine-2-carboxamide, 2fli, 2-fly, f-ligrlo-nh2, 2-fap, 2-f-ligrlo-nh2, d0n2vn, 2-furoyl-ligrlo-amide trifluoroacetate salt, 2-furoyl-leu-ile-gly-arg-leu-orn-nh2 trifluoroacetate salt
PubChem CID 714286
IUPAC Name 3-amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
SMILES CC1=CC(=NC2=C1C(=C(S2)C(=O)NCC3=CC=C(C=C3)Cl)N)C

Specifications

Quantity 10 mg
Formula Weight 345.85
Percent Purity >99%
Chemical Name or Material VU 10010
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