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VU 152100, Tocris Bioscience™

Product Code. 18054722
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Positive allosteric modulator of M4 receptors

Selective positive allosteric modulator of M4 muscarinic acetylcholine receptors (mAChRs) (EC50 = 380 nM). Induces 21-fold shift in ACh potency at M4 receptor. Displays no activity at other mAChR subtypes.

Chemical Identifiers

CAS 409351-28-6
Molecular Formula C18H19N3O2S
Molecular Weight (g/mol) 341.429
InChI Key MDNWGCQSCGNTKH-UHFFFAOYSA-N
Synonym 3-amino-n-4-methoxyphenyl methyl-4,6-dimethylthieno 2,3-b pyridine-2-carboxamide, 3-amino-n-4-methoxybenzyl-4,6-dimethylthieno 2,3-b pyridine carboxamide, kinome_1269, d0k3hy, vu hplc, 3-amino-4,6-dimethyl-n-p-anisyl-thieno 2,3-b pyridine-2-carboxamide, 3-amino-4,6-dimethylthiopheno 2,3-b pyridin-2-yl-n-4-methoxyphenyl methyl carboxamide, 3-amino-n-4-methoxyphenyl methyl-4,6-dimethyl-2-thieno 2,3-b pyridinecarboxamide, 3-amino-n-4-methoxyphenyl methyl-4,6-dimethyl-thieno 2,3-b pyridine-2-carboxamide, 3-amino-n-4-methoxyphenyl methyl-4,6-dimethylthieno 5,4-b pyridine-2-carboxamide
PubChem CID 864492
IUPAC Name 3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
SMILES CC1=CC(=NC2=C1C(=C(S2)C(=O)NCC3=CC=C(C=C3)OC)N)C

Specifications

Quantity 10 mg
Formula Weight 341.43
Percent Purity >98%
Chemical Name or Material VU 152100
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