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(-)-Xestospongin C, Tocris Bioscience™
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Quantity:
10 μg
Description
Reported inhibitor of IP3-dependent Ca2+ release. Inhibits bradykinin -induced Ca2+ release in PC12 cells and attenuates PHP-induced IL-2 production in Jurkat T cells. Exhibits no effect on ryanodine receptor-mediated Ca2+ release in PC12 cells. Does not interact with the IP3 binding site. Recently shown to be an ineffective antagonist of IP3-evoked Ca2+ release in IP3 receptor expressing DT40 cells. Cell permeable.
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Specifications
Specifications
CAS | 88903-69-9 |
Molecular Formula | C28H50N2O2 |
Quantity | 10 μg |
Synonym | (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine |
InChI Key | PQYOPBRFUUEHRC-FRZROCRGSA-N |
SMILES | C1CCCC2CCN3CCCC(C3O2)CCCCCCC4CCN5CCCC(C5O4)CC1 |
Molecular Weight (g/mol) | 446.72 |
PubChem CID | 51026240 |
Formula Weight | 446.71 |
Percent Purity | >98% |
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