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Tocris Bioscience™ XL 184

Potent VEGFR inhibitor; also inhibits other RTKs

Brand:  Tocris Bioscience™ 5422/50

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Product Code. 18734909

  • 1015.00€ / 50mg
Estimated Shipment: 29-01-2025
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Description

Description

XL 184 is a potent VEGFR inhibitor (IC50 = 0.035 nM); also inhibits c-Met, KIT, RET, FLT4, AXL, FLT3, FLT1 and Tie2 (IC50 values are 1.3, 4.6, 5.2, 6, 7, 11.3, 12 and 14.3 nM, respectively). Induces intratumoral hypoxia and apoptosis. Reduces tumor invasion and metastasis in vivo. Antiangiogenic.
Specifications

Specifications

>98%
50 mg
501.51
Cabozantinib, BMS 907351
XL 184
XL 184
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