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(Z)-Pugnac, Tocris Bioscience™

Product Code. 18003962
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Quantity:
10 mg
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This item is not returnable. View return policy

Description

O-GlcNAcase and β-hexosaminidase inhibitor

O-GlcNAc-β-N-acetylglucosaminidase (O-GlcNAcase) and β-hexosaminidase inhibitor (Ki values are 46 and 36 nM respectively) that increases O-GlcNAc levels ∽ 2-fold in HT29 cells. Z-linked isomer is more potent than the E isomer.

Specifications

CAS 132489-69-1
Molecular Formula C15H19N3O7
MDL Number MFCD00145022
Quantity 10 mg
Synonym pugnac, nac-lapco, z-pugnac, n-acetylglucosaminono-1,5-lactone o-phenylcarbamoyl oxime, o-2-acetamido-2-deoxyglucopyranosylidene amino n-phenylcarbamate, 1z-2-acetylamino-2-deoxy-n-phenylamino carbonyl oxy-d-gluconimidic acid delta-lactone, o-2-acetamido-2-deoxy-d-glucopyranosylidene amino n-phenyl carbamate, d-gluconimidic acid, 2-acetylamino-2-deoxy-n-phenylamino carbonyl oxy-, delta-lactone, 1z, 2cbj, 2oxn
InChI Key PBLNJFVQMUMOJY-JXZOILRNSA-N
SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O\C1=N/OC(=O)NC1=CC=CC=C1
IUPAC Name [(2Z,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-ylidene]amino N-phenylcarbamate
Molecular Weight (g/mol) 353.33
PubChem CID 9576811
Formula Weight 353.33
Percent Purity >99%
Chemical Name or Material (Z)-Pugnac
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