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Description
Bradycardic agent that produces use-dependent inhibition of hyperpolarization-activated current If (HCN channel) in sinoatrial node cells (EC50 = 480 nM) and Purkinje fibres. Displays negative chronotropic activity in isolated guinea pig atria (EC50 of 13.4 μM).

Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 493.04 |
Percent Purity | >98% |
Chemical Name or Material | Zatebradine hydrochloride |
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Zatebradine hydrochloride, Tocris Bioscience™ >
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