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Tocris Bioscience™ B I09

IRE1 endonuclease inhibitor; cell permeable

Brand:  Tocris Bioscience™ 6009/10

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Product Code. 18705909

  • 303.00€ / 10mg
Estimated Shipment: 03-03-2025
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Description

Description

B I09 is an IRE-1 RNase inhibitor (IC50 = 1.23 μM). Inhibits IRE-1/XBP1 pathway. Cell permeable. Inhibits growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model.
Specifications

Specifications

Beige
1607803-67-7
303.31g/mol
Store at -20°C
10 mg
Inhibitor
C16H17NO5
Soluble to 50mM in DMSO
Inhibits Rnase
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