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BAY 678
Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor
Brand: Tocris Bioscience 5706/25
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Description
BAY 678 is a potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM). Exhibits around 2000-fold selectivity for NHE against a panel of 21 other serine proteases. Effective in an acute lung injury model in vivo. Orally bioavailable. Inactive S-enantiomer (Cat.No.6389) also available.
Specifications
| 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile | |
| >98% | |
| C20H15F3N4O2 |
| 675103-36-3 | |
| 25 mg | |
| Observed MW: 400.35 |
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Product Title
BAY 678 > 25mg
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