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BAY 678
Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor
118.00€ - 455.00€
Specifications
| Chemical Name or Material | 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile |
|---|---|
| CAS | 675103-36-3 |
| Assay Percent Range | >98% |
| Molecular Formula | C20H15F3N4O2 |
| Formula Weight | Observed MW: 400.35 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18741429
|
Tocris Bioscience
5706/25 |
25 mg |
455.00€
25mg |
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|
18739278
|
Tocris Bioscience
5706/5 |
5 mg |
118.00€
5mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor (IC50 = 20 nM). Exhibits around 2000-fold selectivity for NHE against a panel of 21 other serine proteases. Effective in an acute lung injury model in vivo. Orally bioavailable. Inactive S-enantiomer (Cat.No.6389) also available.Specifications
| 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile | |
| >98% | |
| Observed MW: 400.35 |
| 675103-36-3 | |
| C20H15F3N4O2 |
Safety and Handling
Recommended Storage : Store at -20°C
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Product Title
BAY 678