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DiscoverX cAMP Hunter™ CHO-K1 GPR35 Gi Cell Line
The cAMP Hunter™ CHO-K1 GPR35 Gi Cell Line measures GPR35 (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 95-0152C2
This item is not returnable.
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Description
The cAMP Hunter GPR35 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. zaprinast) based activation of GPR35 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype GPR35 , a naturally Gi/Go coupled GPCR. Upon activation of GPR35 , the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Intracellular cAMP level | |
| Cell Lines | |
| 2 Vials | |
| NM_005301 |
| CHO-K1 | |
| Zaprinast | |
| GPR35 |
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DiscoverX cAMP Hunter™ CHO-K1 GPR35 Gi Cell Line
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