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The PathHunter™ Jurkat NFAT Pathway Reporter Cell Line measures NFAT pathway activation through detection of induced expression levels of a tagged reporter protein. This cell line ships as two vials of cryopreserved cells.
The KILR™ MOLT-4 Cell Pool allows for assay of effector-induced cell death by a variety of immune mechanisms. This cell pool ships as two vials of cryopreserved cells.
The ChemiScreen™ CB1 Cannabinoid Receptor Membrane Preparation allows measurement of ligand binding to CNR1 GPCR via radioligand binding assays, or GPCR activity via GTPγS assay. Membrane preps contain 1mL of 1mg/mL frozen membranes.
The PathHunter™ Jurkat PD-1 Signaling Assay (SHP-2) measures PD-1 signal by recruitment of SH2 domain protein to the activated receptor. This cell line ships as two vials of cryopreserved cells.
The PathHunter™ U2OS GPR22 β-Arrestin Orphan GPCR Cell Line measures GPR22 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.
The Ready-to-Assay™ P2Y4 Purinergic Receptor Frozen Cells measure P2RY4 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
The ChemiBrite™ FSH Glycoprotein Hormone Receptor Stable Cell Line measures FSHR (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
The Ready-to-Assay™ GLP-1 Receptor Frozen Cells measure GLP1R (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
The Ready-to-Assay™ mGlu2 Metabotropic Glutamate Receptor Frozen Cells measure GRM2 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
The Ready-to-Assay™ SST5 Somatostatin Receptor Frozen Cells measure SSTR5 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
The Ready-to-Assay™ IP1 Prostanoid Receptor Frozen Cells measure PTGIR (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
The ChemiScreen™ V1A Vasopressin Receptor Membrane Preparation allows measurement of ligand binding to AVPR1A GPCR via radioligand binding assays. Membrane preps contain 1mL of 1mg/mL frozen membranes.