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DiscoverX Ready-to-Assay™ P2Y4 Purinergic Receptor Frozen Cells
The Ready-to-Assay™ P2Y4 Purinergic Receptor Frozen Cells measure P2RY4 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
Brand: DiscoverX HTS211RTA
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Description
The Ready-to-Assay™ P2Y4 Purinergic Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. ATP, UTP) based activation of P2RY4 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress P2RY4 , a naturally Gq coupled GPCR. Upon activation of P2RY4 , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.Specifications
| P2Y4 | |
| ATP, UTP | |
| P2RY4 |
| Frozen Cells | |
| 2 Vials of Cells |
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DiscoverX Ready-to-Assay™ P2Y4 Purinergic Receptor Frozen Cells
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