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DiscoverX PathHunter™ Jurkat NFAT Pathway Reporter Cell Line
The PathHunter™ Jurkat NFAT Pathway Reporter Cell Line measures NFAT pathway activation through detection of induced expression levels of a tagged reporter protein. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1141C19
This item is not returnable.
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Description
The PathHunter™ Jurkat NFAT Pathway Reporter Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting the NFAT pathway. This cell line enables assessment of NFAT pathway stimulation based on changes in the expression of a NFAT response element-driven reporter protein. This product uses EFC technology. The included cell line expresses PL-tagged reporter protein under the control of a NFAT pathway-inducible transcriptional response element. Pathway activation induces expression of the PL-tagged protein, allowing detection of EFC signal upon addition of EA-containing detection reagent. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| NFAT pathway stimulation | |
| Cell Lines | |
| 2 Vials |
| Jurkat | |
| Anti-CD3 antibody [OKT3] | |
| NFAT |
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DiscoverX PathHunter™ Jurkat NFAT Pathway Reporter Cell Line
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