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DiscoverX cAMP Hunter™ CHO-K1 HTR1A Gi Cell Line

The cAMP Hunter™ CHO-K1 HTR1A Gi Cell Line measures HTR1A (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.

Brand:  DiscoverX 95-0132C2

Encompass

Product Code. 17314659

  • 19183.50€ / 2 ampoules

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Description

Description

The cAMP Hunter HTR1A Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin/5-HT) based activation of HTR1A GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype HTR1A , a naturally Gi/Go coupled GPCR. Upon activation of HTR1A , the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.
Specifications

Specifications

Intracellular cAMP level
Cell Lines
2 Vials
NM_000524.2
CHO-K1
Serotonin/5-HT
HTR1A
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