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DiscoverX cAMP Hunter™ CHO-K1 TSHR (Long Isoform) Gs Cell Line
The cAMP Hunter™ CHO-K1 TSHR (Long Isoform) Gs Cell Line measures TSHRL (GPCR) activity via increased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 95-0153C2
This item is not returnable.
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Description
The cAMP Hunter TSHRL Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. TSH) based activation of TSHRL GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype TSHRL , a naturally Gs coupled GPCR. Upon activation of TSHRL , the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Intracellular cAMP level | |
| Cell Lines | |
| 2 Vials | |
| NM_000369.2 |
| CHO-K1 | |
| TSH, Thyroid stimulating hormone, Human | |
| TSHRL |
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