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DiscoverX cAMP Hunter™ CHO-K1 VIPR2 Gs Cell Line
The cAMP Hunter™ CHO-K1 VIPR2 Gs Cell Line measures VIPR2 (GPCR) activity via increased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 95-0052C2
This item is not returnable.
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Description
The cAMP Hunter VIPR2 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. VIP) based activation of VIPR2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype VIPR2 , a naturally Gs coupled GPCR. Upon activation of VIPR2 , the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Intracellular cAMP level | |
| Cell Lines | |
| 2 Vials | |
| NM_003382 |
| CHO-K1 | |
| VIP, Human | |
| VIPR2 |
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