missing translation for 'onlineSavingsMsg'
Learn More
Learn More
DiscoverX ChemiScreen™ M4 Muscarinic Acetylcholine Receptor Stable Cell Line
The ChemiScreen™ M4 Muscarinic Acetylcholine Receptor Stable Cell Line measures CHRM4 (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX HTS117C
This item is not returnable.
View return policy
Description
The ChemiScreen™ M4 Muscarinic Acetylcholine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. acetylcholine) based activation of CHRM4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM4 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM4 , the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Calcium Flux | |
| Cell Lines | |
| 2 Vials | |
| NM_000741.2 |
| Chem-4 | |
| Acetylcholine | |
| CHRM4 |
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
DiscoverX ChemiScreen™ M4 Muscarinic Acetylcholine Receptor Stable Cell Line
Spot an opportunity for improvement?Share a Content Correction