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DiscoverX CHO-K1 PTAFR Gq Cell Line
The CHO-K1 PTAFR Gq Cell Line measures PTAFR (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 95-0091C2
This item is not returnable.
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Description
The PTAFR Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PAF) based activation of PTAFR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTAFR , a naturally Gq coupled GPCR. Upon activation of PTAFR , the resulting calcium activity can be fluorescently assayed using the Calcium NoWash PLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Intracellular cAMP level | |
| Cell Lines | |
| 2 Vials | |
| NM_000952.4 |
| CHO-K1 | |
| PAF | |
| PTAFR |
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