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DiscoverX HEK 293 HTR2B Gq Cell Line
The HEK 293 HTR2B Gq Cell Line measures HTR2B (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 95-1024C1
This item is not returnable.
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Description
The HTR2B Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin) based activation of HTR2B GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HTR2B , a naturally Gq coupled GPCR. Upon activation of HTR2B , the resulting calcium activity can be fluorescently assayed using the Calcium NoWash PLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
Calcium Signaling | |
Cell Lines | |
2 Vials | |
NM_000867.4 |
293H | |
Serotonin/5-HT | |
HTR2B |
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