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Gibco™ Human IL-13 Recombinant Protein, PeproTech®
E. coli Recombinant Protein
Specifications
| Accession Number | P35225 |
|---|---|
| For Use With (Application) | ELISA, Functional Assay, Western Blot |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 3596 |
| Molecular Weight (g/mol) | 12.6 |
Description
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.Specifications
| P35225 | |
| protein with no preservative | |
| 12.6 | |
| E. coli | |
| RUO | |
| ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600 | |
| Human | |
| Recombinant | |
| Lyophilized |
| ELISA, Functional Assay, Western Blot | |
| 3596 | |
| Human IL-13 | |
| -20°C | |
| <1 EU/μg | |
| Il13 | |
| Unconjugated | |
| MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |