missing translation for 'onlineSavingsMsg'
Learn More
Learn More
DiscoverX InCELL Hunter™ A549 CLK2 Kinase Binding Cell Line
The InCELL Hunter™ A549 CLK2 Kinase Binding Cell Line measures target engagement via compound-induced stabilization of CLK2 target protein. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 96-0057C15
This item is not returnable.
View return policy
Description
The InCELL Hunter™ A549 CLK2 Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of CLK2 via detection of CLK2 levels. This product uses EFC technology. The cell line included overexpresses CLK2 target protein fused to PL. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Target Engagement | |
| Cell Lines | |
| CLK2 |
| A549 | |
| 2 Vials |
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction