missing translation for 'onlineSavingsMsg'
Learn More
Learn More
DiscoverX PathHunter™ CHO-K1 CXCR7 (CMKOR1) β-Arrestin Cell Line
The PathHunter™ CHO-K1 CXCR7 (CMKOR1) β-Arrestin Cell Line measures CXCR7 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-0248C2
This item is not returnable.
View return policy
Description
The PathHunter™ CXCR7 (CMKOR1) β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL12/SDF-1α) based activation of CXCR7 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged CXCR7 and EA-tagged β-Arrestin 2. Activation of CXCR7 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| β-Arrestin recruitment | |
| Cell Lines | |
| 2 Vials | |
| NM_020311.2 |
| CHO-K1 | |
| Recombinant Human SDF-1α (CXCL12) | |
| CXCR7 (CMKOR1) |
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
DiscoverX PathHunter™ CHO-K1 CXCR7 (CMKOR1) β-Arrestin Cell Line
Spot an opportunity for improvement?Share a Content Correction