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DiscoverX PathHunter™ CHO-K1 mPTGIR β-Arrestin Cell Pool
The PathHunter™ CHO-K1 mPTGIR β-Arrestin Cell Pool measures mPTGIR (GPCR) activity via recruitment of β-Arrestin2. This cell pool ships as two vials of cryopreserved cells. Mouse protein.
Brand: DiscoverX 93-0615P2
This item is not returnable.
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Description
The PathHunter™ mPTGIR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin I2, beraprost) based activation of mPTGIR GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged mPTGIR and EA-tagged β-Arrestin 2. Activation of mPTGIR stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable cell pool is provided as two vials of cryopreserved cells. Please note that this product expresses the mouse version of this protein.Specifications
| β-Arrestin recruitment | |
| Cell Pools | |
| mPTGIR |
| CHO-K1 | |
| 2 Vials |
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