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DiscoverX PathHunter™ CHO-K1 NPY2R β-Arrestin Cell Line
The PathHunter™ CHO-K1 NPY2R β-Arrestin Cell Line measures NPY2R (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-0212C2
This item is not returnable.
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Description
The PathHunter™ NPY2R β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. peptide YY) based activation of NPY2R GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged NPY2R and EA-tagged β-Arrestin 2. Activation of NPY2R stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| β-Arrestin recruitment | |
| Cell Lines | |
| 2 Vials | |
| AY236540 |
| CHO-K1 | |
| Peptide YY, Human | |
| NPY2R |
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DiscoverX PathHunter™ CHO-K1 NPY2R β-Arrestin Cell Line
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