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DiscoverX PathHunter™ DLD1 IL7R/CRLF2 Dimerization Cell Line
The PathHunter™ DLD1 IL7R/CRLF2 Dimerization Cell Line measures ligand-induced dimerization of IL7R/CRLF2 . This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1019C13
This item is not returnable.
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Description
The PathHunter™ IL7R/CRLF2 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. TSLP) induced dimerization of IL7R/CRLF2 receptors. This product uses EFC technology. The cell line included overexpresses IL7R target protein fused to PK alongside CRLF2 target protein fused to EA. Upon ligand-induced dimerization of IL7R/CRLF2, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Dimerization | |
| Cell Lines | |
| 2 Vials | |
| NM_002185.3 |
| DLD1 | |
| TSLP | |
| IL7R/CRLF2 |
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