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DiscoverX PathHunter™ HEK 293 GPR152 β-Arrestin Orphan GPCR Cell Line
The PathHunter™ HEK 293 GPR152 β-Arrestin Orphan GPCR Cell Line measures GPR152 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-0384C1A
This item is not returnable.
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Description
The PathHunter™ GPR152 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR152 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged GPR152 and EA-tagged β-Arrestin 2. Activation of GPR152 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Orphan receptor with unknown ligand.Specifications
| β-Arrestin recruitment | |
| Cell Lines | |
| GPR152 |
| 293H | |
| 2 Vials | |
| NM_206997.1 |
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