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DiscoverX PathHunter™ HEK 293 RELA Nuclear Translocation Cell Line
The PathHunter™ HEK 293 RELA Nuclear Translocation Cell Line measures NFκB pathway activation via nuclear translocation of RELA. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-0907C1
This item is not returnable.
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Description
The PathHunter™ HEK 293 RELA Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the NFκB pathway. This cell line enables assessment of ligand (e.g. wortmannin) based pathway activation via detection of resulting RELA nuclear translocation. This product uses EFC technology. The included cell line overexpresses PL-tagged RELA and nuclear localized EA. Upon pathway activation, induced nuclear translocation of RELA leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| RELA nuclear translocation | |
| Cell Lines | |
| 2 Vials | |
| NM_021975 |
| 293H | |
| IL-1α | |
| NFκB |
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