missing translation for 'onlineSavingsMsg'
Learn More
Learn More
DiscoverX PathHunter™ NMBR Total GPCR Internalization U2OS Cell Line
The PathHunter™ NMBR Total GPCR Internalization U2OS Cell Line measures NMBR (GPCR) internalization via early-endosome localization. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-0939C3
This item is not returnable.
View return policy
Description
The PathHunter™ NMBR Total GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line enables assessment of ligand (e.g. neuromedin B) based internalization of NMBR via detection of localization to the early endosome. This product uses EFC technology. The included cell line overexpresses PK-tagged NMBR and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the NMBR receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Receptor Internalization | |
| Cell Lines | |
| 2 Vials | |
| NM_002511.2 |
| U2OS | |
| Neuromedin B (porcine) | |
| NMBR |
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
DiscoverX PathHunter™ NMBR Total GPCR Internalization U2OS Cell Line
Spot an opportunity for improvement?Share a Content Correction
