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DiscoverX PathHunter™ U2OS BMPR1B/BMPR2 Dimerization Cell Line
The PathHunter™ U2OS BMPR1B/BMPR2 Dimerization Cell Line measures ligand-induced dimerization of BMPR1B/BMPR2 . This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1053C3
This item is not returnable.
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Description
The PathHunter™ BMPR1B/BMPR2 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. BMP-6) induced dimerization of BMPR1B/BMPR2 receptors. This product uses EFC technology. The cell line included overexpresses BMPR1B target protein fused to PK alongside BMPR2 target protein fused to EA. Upon ligand-induced dimerization of BMPR1B/BMPR2 , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Dimerization | |
| Cell Lines | |
| 2 Vials | |
| NM_001256793.1 |
| U2OS | |
| BMP-6 | |
| BMPR1B/BMPR2 |
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