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DiscoverX PathHunter™ U2OS CDC25A Degradation Cell Line
The PathHunter™ U2OS CDC25A Degradation Cell Line measures pathway activation-induced degradation of CDC25A target protein. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-0765C3
This item is not returnable.
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Description
The PathHunter™ U2OS CDC25A Degradation Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting the cell cycle checkpoint pathway. This cell line enables detection of levels of CDC25a, allowing for assessment of CHK-1-activation-induced CDC25a degradation. This product uses EFC technology. The cell line included overexpresses CDC25a target protein fused to PL. EA is contained in the detection reagent. Upon pathway-activation-induced degradation of CDC25a EFC signal is lost. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| CDC25A Degradation | |
| Cell Lines | |
| 2 Vials | |
| NM_001789.2 |
| U2OS | |
| Doxorubicin Hydrochloride | |
| CDC25A |
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Product Title
DiscoverX PathHunter™ U2OS CDC25A Degradation Cell Line
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