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DiscoverX PathHunter™ U2OS CSF2RB/CSF2RA Dimerization Cell Line
The PathHunter™ U2OS CSF2RB/CSF2RA Dimerization Cell Line measures ligand-induced dimerization of CSF2RB/CSF2RA . This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1078C3
This item is not returnable.
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Description
The PathHunter™ CSF2RB/CSF2RA Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. GM-CSF) induced dimerization of CSF2RB/CSF2RA receptors. This product uses EFC technology. The cell line included overexpresses CSF2RB target protein fused to PK alongside CSF2RA target protein fused to EA. Upon ligand-induced dimerization of CSF2RB/CSF2RA , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Dimerization | |
| Cell Lines | |
| 2 Vials | |
| NM_000395.2 |
| U2OS | |
| GM-CSF | |
| CSF2RB/CSF2RA |
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