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DiscoverX PathHunter™ U2OS EGFR/ErbB2 Dimerization Cell Line
The PathHunter™ U2OS EGFR/ErbB2 Dimerization Cell Line measures ligand-induced dimerization of EGFR/ErbB2 . This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1051C3
This item is not returnable.
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Description
The PathHunter™ EGFR/ErbB2 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. EGF) induced dimerization of EGFR/ErbB2 receptors. This product uses EFC technology. The cell line included overexpresses ErbB2 target protein fused to PK alongside EGFR target protein fused to EA. Upon ligand-induced dimerization of EGFR/ErbB2 , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Dimerization | |
| Cell Lines | |
| 2 Vials | |
| NM_005228.3 |
| U2OS | |
| Recombinant Human EGF | |
| EGFR/ErbB2 |
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