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DiscoverX PathHunter™ U2OS ErbB2/ErbB3 Dimerization Cell Line
The PathHunter™ U2OS ErbB2/ErbB3 Dimerization Cell Line measures ligand-induced dimerization of ErbB2/ErbB3 . This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1042C3
This item is not returnable.
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Description
The PathHunter™ ErbB2/ErbB3 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. neuregulin-1 Beta 2) induced dimerization of ErbB2/ErbB3 receptors. This product uses EFC technology. The cell line included overexpresses ErbB2 target protein fused to PK alongside ErbB3 target protein fused to EA. Upon ligand-induced dimerization of ErbB2/ErbB3, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Dimerization | |
| Cell Lines | |
| 2 Vials | |
| NM_004448.2 |
| U2OS | |
| Recombinant Human Neuregulin-1 Beta 2 | |
| ErbB2/ErbB3 |
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