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DiscoverX PathHunter™ U2OS IL20R1/IL20R2 Dimerization Cell Line
The PathHunter™ U2OS IL20R1/IL20R2 Dimerization Cell Line measures ligand-induced dimerization of IL20R1/IL20R2 . This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-1027C3
This item is not returnable.
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Description
The PathHunter™ IL20R1/IL20R2 Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-24) induced dimerization of IL20R1/IL20R2 receptors. This product uses EFC technology. The cell line included overexpresses IL20R2 target protein fused to PK alongside IL20R1 target protein fused to EA. Upon ligand-induced dimerization of IL20R1/IL20R2 , detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
Dimerization | |
Cell Lines | |
2 Vials | |
NM_014432.3 |
U2OS | |
IL-24 | |
IL20R1/IL20R2 |
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