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DiscoverX PathHunter™ U2OS PRβ Nuclear Translocation Cell Line
The PathHunter™ U2OS PRβ Nuclear Translocation Cell Line measures PRβ nuclear hormone receptor activation via nuclear translocation. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 93-0484C3
This item is not returnable.
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Description
The PathHunter™ PRβ Nuclear Translocation cell line is a stable, engineered cell line for use in studying drug candidates affecting NHR activation and nuclear translocation. This cell line enables assessment of ligand (e.g. testosterone, norgestrel) based NHR activation via detection of resulting PRβ nuclear translocation. This product uses EFC technology. The included cell line overexpresses PL-tagged PRβ NHR and nuclear localized EA. Upon activation of PRβ, induced nuclear translocation leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
| Translocation | |
| Cell Lines | |
| 2 Vials | |
| NM_000926 |
| U2OS | |
| D(-)-Norgestrel | |
| PRβ |
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