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Tocris Bioscience™ MK6-83

TRPML channel activator

Brand: Tocris Bioscience™ 5547/10

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Product Code. 18703439

245.00€ / 10mg

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Description

MK6-83 is a TRPML channel activator (EC50 = 110 nM). Also activates F408Δ and F465L TRPML mutants (EC50 values are 0.1 and 1.23 μM respectively). Restores endolysosomal trafficking and zinc homeostasis in lysosomes of mucolipidosis type IV (MLIV) mutant fibroblasts.

Specifications

Chemical Name or Material	MK6-83
Synonym	5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide
Solubility	Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight	336.47
Product Type	Bioactive Small Molecule

CAS	1062271-24-2
Quantity	10 mg
Molecular Formula	C₁₆H₂₀N₂O₂S₂
Physical Form	Solid
Purity	>98%

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Tocris Bioscience™ MK6-83

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